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         Figure 13.1 Carbon monoxide blood saturation [2].

            The main danger from CO is due to its toxicity. It has a great affinity for the hemo-
         globin in the blood with which it forms a permanent bond dcalled carboxyhemoglo-
         bin (COHb). If the blood saturation by COHb increases, various symptoms become
         apparent, and they are listed in Table 13.2. The rate of saturation depends on CO level
         in mine air. If the CO concentration is 1% (10,000 ppm), death can occur in a minute.
         Death can also occur at 70%e80% blood saturation with COHb (Table 13.1).
            Fig. 13.1 shows gradual blood saturation as a function of CO concentration and
         exposure time [2].


         Table 13.2 Gradual CO Poisoning of Blood and Symptoms

          Blood Saturation
          (% COHb)        Symptoms
          5e10            First noticeable effect, loss of some cognitive function.
          10e20           Tightness across forehead, possible headache.
          20e30           Headache, throbbing in temples.
          30e40           Severe headache, weakness, dizziness, dimness of vision, nausea and
                            vomiting, and collapse
          40e60           Increased likelihood of collapse and unconsciousness, coma with
                            intermittent convulsions.
          60e70           Coma, possible death.
          70e80           Respiratory failure, death.
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