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434                                               14  Indoor Air Quality

              into Eq. (14.2), we get

                                        2:08
                                      !              2:08
                                   0:1        2  0:1           3
                                 N
                          c ¼ 10          ¼ 10         ¼ 100=m

                           p
                                    d   p       0:1
                                             3
              Since the volume of the room is 300 m , the total number of particles larger than
            100 nm in diameter cannot exceed 30,000 in total. That is an extremely clean room!
              For the ease of practice, the cleanroom classes and their corresponding maxi-
            mum particle number concentrations are computed using Eq. (14.2) and they are
            summarized in Table 14.3. In this table, the values are the maximum concentrations
            for the particles size or greater. The greater the class number, the higher allowable
            particle concentration can be.
              For a given class, all limits for all particles sizes must be satisfied. For a Class 1
            clean room, the concentration of particles greater than 0.2 μm should be 2 or less
                    3
                                                                       3
            particle/m . Meanwhile, the particles ≥0.1 μm should not exceed 10 #/m .
              Cleanroom is important to the quality of many industries, such as medical,
            manufacturing, and packaging. Cleanrooms were first developed for aerospace
            applications to manufacture and assemble satellites, missiles, and aerospace elec-
            tronics. Most applications involve clean airspaces of large volumes with cleanliness
            levels of ISO Class 9 or cleaner. Recent advances in electronics industries continue
            to drive the design of cleanrooms. Most recently designed semiconductor clean
            rooms are ISO Class 5 or cleaner. In addition, preparation of pharmaceutical,
            biological, and medical products all require clean airspaces to control airborne
            bacteria and viruses to prevent contamination. Furthermore, some operating rooms
            in hospital may be classified as cleanrooms, but their primary function is to limit
            particular types of contamination rather than the quantity of particles.



            Table 14.3 Cleanroom classes
                                                         3
            ISO class    Maximum particle number concentration (#/m ) for particle size
            number (N)             2:08
                         c ¼ 10 N 0:1

                          p      d
                                 p
                         0.1 μm    0.2 μm  0.3 μm   0.5 μm    1 μm      5 μm
            ISO Class 1  10        2
            ISO Class 2  100       24      10       4
            ISO Class 3  1,000     237     102      35        8
            ISO Class 4  10,000    2,370   1,020    352       83
            ISO Class 5  100,000   23,700  10,200   3,520     832       29
            ISO Class 6  1,000,000  237,000  102,000  35,200  8,320     293
            ISO Class 7                             352,000   83,200    2,930
            ISO Class 8                             3,520,000  832,000  29,300
            ISO Class 9                             35,200,000  8,320,000  293,000
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