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108                                Biobehavioral Resilience to Stress

                             (improve unit cohesion), physical fitness (cardiovascular health), stress man-

                             agement techniques (meditation, relaxation), and cognitive behavioral train-
                             ing (orientation to optimism and cognitive reframing). Ideally, such training
                             should be accompanied by efforts to reduce allostatic load by discouraging

                             unhealthy lifestyle choices (smoking, alcohol consumption, sleep depriva-
                             tion, poor nutrition).

                                The information considered in this chapter also suggests that it may be
                             useful to consider new pharmacological approaches to the treatment or pre-

                             vention of traumatic stress effects. Of particular interest would be the devel-

                             opment of agents that can effectively stabilize HPA function and reduce SNS
                             reactivity. For example, CRF antagonists could exert anxiolytic, antidepres-

                             sant, and preventive effects against the development of stress-induced mood
                             and anxiety-related disorders. Additionally, it would be reasonable to predict
                             that agents that help to contain stress-related SNS activation (e.g., agents that
                             modulate NPY and NE release) would thereby enhance resilience to stress.
                             Pharmacologic intervention may prove a useful complement to relaxation
                             techniques and cognitive behavioral therapies that bolster capacity to modu-
                             late limbic activity.
                                Because military life and service can be demanding, stressful, and some-
                             times traumatizing, it is important to pursue research and applications
                             toward reducing allostatic load and thus promoting the psychological and
                             physical resilience of service members.



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