Page 61 - Biobehavioral Resilence to Stress
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38                                 Biobehavorial Resilience to Stress

                             exposure to combat and likelihood of developing PTSD symptoms. Specifi -
                             cally, PTSD prevalence ranged from as low as 4.5% among service members
                             who were never involved in a fi refight to as high as 19.3% among those who

                             had been involved in at least fi ve fi refi ghts.
                                Anxiety disorders may be treated by clinical therapies such as cogni-
                             tive behavioral therapy, exposure therapy, and eye movement desensitiza-

                             tion and reprocessing (EMDR) therapy. These methods are particularly


                             effective in treating ASD and PTSD but may be difficult to perform in a

                             combat zone as mission or travel requirements may interfere with the need
                             for weekly  therapeutic sessions over a sustained period of time. For service
                             members who must be treated while serving in the theater of operations,
                             therapy  usually focuses on alleviating specific symptoms that interfere with

                               performance in the fi eld.
                                Interestingly, symptoms such as hypervigilance can be seen as highly
                              adaptive and even essential to survival while in combat and thus may not
                              indicate the need for intervention or treatment until the postdeployment
                             phase. If medical intervention is indicated for anxiety disorder, SSRIs are
                               usually the preferred pharmaceutical approach (APA Practice Guide-
                             lines, 2004; Ball, Kuhn, Wall, Shekhar & Goddard, 2005; Stahl, 2000).
                               Benzodiazepines may also be helpful in the treatment of panic disorder.

                             However, caution is  warranted in light of recent findings, which suggest that
                             benzodiazepines can actually increase the severity of PTSD, especially if
                             used for a long period of time (APA Practice Guidelines, 2004). Venlafaxine

                             (Effexor XR) may be  useful in treating GAD with depression (Howland &
                             Thase, 2005; Thase, Entsuah & Rudolph, 2001).


                             Sleep Disorders
                             Insomnia has been the most commonly reported symptom of combat-related
                             stress among service members deployed in Iraq. Since prolonged sleep

                              deprivation can have a potentially critical effect on performance (see Belenky
                             et al., 1994), it is a common focus for treatment in a combat zone. In the
                             absence of other symptoms indicative of underlying medical issues, insomnia

                             can be treated first by behavioral intervention (e.g., sleep hygiene  education).
                             If pharmaceutical intervention becomes necessary, drug selection must take

                             into account possible side effects (e.g., drowsiness),  personnel occupation and
                             current duties, comorbid symptoms if any,  history of substance abuse if any,


                             and individual limitations or difficulties that might interfere with eff ective
                             self-administration of medication according to instructions. Deployment
                             formulary medications for the treatment of insomnia include trazodone,
                              zolpidem, lorazepam, clonazepam, prazosin, and quetiapine. As an adjunct
                             in the treatment of ASD and PTSD, alpha- or beta-blocker medications can
                             be used to target autonomic symptoms and nightmares.






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