Page 116 - Color Atlas of Biochemistry

Enzymes 107

A. Redox coenzymes 2

Coenzyme Oxidized form Reduced form Type Trans- E ol
ferred

6. Lipoamide P 2[H] –0.29
S S H H
HC CH S S H
C
S S HS SH HC CH N
H 2 C
H 2 O
ox. red.
7. Iron– [Fe S ] n+ [Fe S ] m+ P 1e –0.6
4 4
2 2
sulfur S Fe to
cluster RS Fe S Fe SR RS Fe S +0.5
RS S SR RS S Fe Fe S
SR
8. Heme P 1e 0
R 2 CH 3 R 2 CH 3 to
+0.5
H 3 C H 3 C
A B R 3 A B R 3
N N N N
Fe 3+ Fe 2+
N N N N
3+ 2+
D C D C
R 1 CH 3 R 1 CH 3
ox. red.
COO COO COO COO

B. Group-transferring coenzymes 1

Coenzyme Free form Charged form Group(s) Important
(symbol) trans- enzymes
ferred

1. Nucleoside P Phospho-
1. phosphates transferases
O O O Base Nucleotidyl-
B-Rib
O P O P O P O CH 2 transferases
O B-Rib- P (2.7.n.n)
O O O Ligases
N H
PP P B-Rib- PP (6.n.n.n)
H H
OH OH

2. Coenzyme A H H CH 3 O Acyl Acyltrans-
CH 2 N C C C CH 2 O P O residues ferases
O
CH 2 O OH CH 3 NH 2 (2.3.n.n)
C O C O O P O N
H N O HC N CoA trans-
H N
CH 2 CH 2 N N ferases
S CH 2 O (2.8.3.n)
A CH 2 H H
S
H H
CH 2 C O
O OH
SH CH 3 O P O
O
3. Thiamine R Hydroxy- Decarboxy-
3. diphosphate H alkyl lases (4.1.1.n)
H 3 C N NH 2 H C OH residues Oxoacid de-
N S hydrogenases
N CH 2 N S (1.2.4. n)
TPP Transketolase
H 3 C CH 2 (2.2.1.1)
H 3 C CH 2 CH 2 O P P

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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