Page 7 - Computational Modeling in Biomedical Engineering and Medical Physics

Contents vii

Arterial flow evaluation 129
A equivalent lumped parameters electric circuit 133
References 135

5. Bioimpedance methods 143
5.1 Introduction 143
5.2 The electrical impedance 144
5.3 The electrical impedance in noninvasive hemodynamic monitoring 147
The plethysmogram 147
Bioimpedance methods and models 148
5.4 Thoracic bioimpedance methods and models 149
The thoracic electrical bioimpedance 149
The electrical velocimetry model and the cardiometry method 150
5.5 The electrical cardiometry—electrical velocimetry 153
The electrical conductivity of the blood 154
Hemodynamic of larger vessels 155
The electromagnetic field 157
5.6 The ECM brachial bioimpedance 161
5.7 Some comments on numerical modeling results 165
References 166

6. Magnetic drug targeting 171
6.1 Introduction 171
6.2 Magnetic nanoparticles for magnetic drug targeting 173
Magnetic properties of materials used in designing the magnetic drug targeting
medication 173
Superparamagnetic iron oxide nanoparticles 174
Superparamagnetic iron oxide nanoparticles synthesis, coating, and
functionalization 176
6.3 Several modeling concerns in magnetic drug targeting 177
6.4 Magnetic drug mixing 179
6.5 Magnetic drug targeting, from the blood vessel to the targeted region 180
Hemodynamic and magnetic field driven mass transfer in larger vessels 182
The constructal optimization of the magnetic field source 185
Using electromagnets for magnetic drug targeting 191
From conceptual to more realistic models 194
6.6 The magnetic drug transfer from the larger blood vessel to the region of interest 199
Biorheological models in magnetic drug transfer 199