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72   Chapter Five


                                     The physiologic effects of currents must be comprehended as they
                                  dictate the minimum safety requirements in electrical installations.


                             5.2 The Human Body as an Electrical System
                                  On a cellular level, the human body is an electrical system, as the flux
                                  of information necessary to its proper functioning is propagated by
                                  the means of electric charges, positive and negative, constituted by
                                  ions. A clear example is the cardiac muscle, whose contractions are
                                  the result of the biological electrical system.

                                  5.2.1 On the Electrical Nature of the Cells
                                  Biological tissues are formed by cells, in contact with each other, im-
                                  mersed in the extracellular (or interstitial) fluid. The cell is enclosed in
                                  a membrane, which contains the intracellular fluid. Both intracellular
                                  and interstitial fluids contain electrically charged ions, whose relative
                                  concentration is indicated by the size of the circles in Fig. 5.1.
                                     Measurements indicate that the charges of the undisturbed cell,
                                  uniformly distributed on each side of the membrane, create a perma-
                                  nent potential difference across the cell, called resting (or membrane)
                                  potential. This voltage can assume a value as high as −70 mV, where
                                  the negative sign indicates that there is an excess of negative charge
                                  inside of the cell, with respect to the interstitial liquid.
                                     The resting potential is the result of the equilibrium between two
                                  different forces. Ions on both sides of the membrane are subject to
                                  the electric field reciprocally exerted by their charges. Ions are also
                                  exposed to the forces of diffusion due to their chemical gradient. Ions,























                                  FIGURE 5.1 Relative concentrations and forces of ions in equilibrium across
                                  the cell’s membrane.
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