Page 82 - Encyclopedia of Chemical Compounds 3 Vols
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H         O

                                                     H          C         C
                                                           C         C          OH

                                                           C         C
                                                     H          C         O


                                                                H         C     CH 3
                                                                     O







                    OTHER NAMES:
              Aspirin; see Overview
                  for more names
                        FORMULA:
                CH 3 COOC 6 H 4 COOH
                                         Acetylsalicylic Acid
                       ELEMENTS:
                Carbon, hydrogen,
                         oxygen


                   Carboxylic acid       OVERVIEW
                        (organic)
                                             Acetylsalicylic acid (uh-SEE-till-sal-in-SILL-ik As-id, or uh-
                  COMPOUND TYPE: KE
                          STATE:  Y      se-TEEL-sal-ih-SEEL-ik AS-id), more commonly known as
                           Solid  F      aspirin, is the world’s most commonly used therapeutic drug.
                                         By one estimate, about 137 million aspirin tablets are taken
                MOLECULAR WEIGHT:  A
                                         every day throughout the world. The drug is also known by
                     180.17 g/mol  C
                                         other names including: o-acetoxybenzoic acid; 2-(acetyloxy)-
                   MELTING POINT:  T     benzoic acid; 2-carboxyphenyl acetate; and benzoic acid,

                     135 C (275 F;       2-hydroxyacetate, in addition to about ten other systematic
                               S
                     decomposes)
                                         names and many common names.
                    BOILING POINT:           The analgesic properties of willow tree bark, from which
                   Not applicable        salicylic acid comes, have been known for well over 3,500
                                         years. They were first described in Egyptian scrolls dating to
                      SOLUBILITY:
                 Soluble in water,       about 1550 BCE and were later recommended by a number of
                    alcohol, ether,      ancient authorities, including the famous Greek physician
                      chloroform         Hippocrates (c. 460–370 BCE), the Roman encyclopedist Aulus
                                         Cornelius Celsus (c. 10 BCE–date of death unknown), the
                                         Roman philosopher Pliny the Elder (23 CE–CE), and the Greek
                                         physician Pedanius Dioscorides (40–90 CE).


                                         CHEMICAL COMPOUNDS                                   31
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