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48   Chapter 2 Deep convolutional neural network in medical image processing




                                    4.2 Eye
                                       Over the past few years, ophthalmic imaging has developed
                                    rapidly. Even then, it is very recently that DL algorithms are being
                                    useful in understanding the eye images. For the examination of
                                    color fundus imaging (CFI), most of the works have used simple
                                    CNNs. It can be observed from Table 2.2 that many of the studies
                                    use fundus photography for better examining the eye. Fundus
                                    photography is a noninvasive process that captures images of
                                    the retina, optic disc, and macula using retinal cameras. It can
                                    be helpful in detecting and monitoring diseases such as diabetic
                                    retinopathy, neoplasms of the retina, glaucoma, and age-related
                                    macular degeneration, and also it plays an important role in iden-
                                    tifying causes of preventable blindness. A wide variety of applica-
                                    tions such as detection and segmentation of retinal diseases,
                                    diagnosis of eye abnormalities, segmentation of different anatom-
                                    ical parts, and image quality assessment have been addressed in
                                    the recent research works.

                                    4.3 Breast
                                       CNN applications were initially used on breast imaging
                                    around the late 1990s. Recently, interest has resumed in this
                                    domain, which has led to important developments over the
                                    state-of-the-art and accomplishing the efficiency. As most of
                                    the breast imaging methodologies are 2D in nature, techniques
                                    that were fruitful in processing natural images can be transferred
                                    with ease. But the lacuna here is that the only problem that is
                                    handled is the detection of breast lesions, which is subdivided
                                    into three tasks. One is the detection and classification of mass-
                                    like lesions, second is the detection and classification of microcal-
                                    cifications, and the third is the risk scoring of breast cancer
                                    images. One of the most commonly used modalities for examina-
                                    tion of the breast is mammography and therefore has gained the
                                    attraction of most researchers. Work related to tomography, ul-
                                    trasound, and shear wave elastography is not much in use, and
                                    thus, these modalities have the possibility of getting more atten-
                                    tion in the coming years. Table 2.2 summarizes the recent
                                    research work done in breast image analysis. As most of the coun-
                                    tries have screening facilities for breast cancer, there should be a
                                    huge amount of data available, mostly for mammography, and so
                                    there is enough scope for DL models to flourish.
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