Page 18 - Handbook of Hazardous Chemical Properties

8 ACRYLAMlDE
and vomiting occur. Loss of consciousness can occur if exposure has been sufficiently great.
Congestion in the chest may be present in varying amounts, and fluid may collect in the lungs
(pulmonary edema) of severely exposed victims. Vapor also causes severe eye irritation (redness,
weeping, and swelling of lids; liquid burns eyes, contact with skin causes reddening or blistering.
Ingestion causes severe irritation of mouth and stomach; General Treament for Exposure: Keep patient
warm and quiet; if conscious, give coffee and call a physician immediately after all types of exposures
to this chemical. INHALATION: Remove patient to fresh air; if breathing becomes difficult, give
oxygen. If breathing has stopped, give artificial respiration. EYES: Immediately flush with plenty of
water for at least 15 min. If medical attention is not immediately available, continue eye irrigation for
another 15 min. period. Upon completion of first 15 min. eye irrigation period, it is permissible to
instill 2 or 3 drops of an effective aqueous local eye amthetic for relief of pain. No oils or ointments
should be used unless so instructed by a physician. SKIN: Flush at once with large amounts of water.
Wash thoroughly with soap and large amounts of water. INGESTION: Have victim drink large amounts
of water. Induce vomiting and keep patient warm and quiet until physician arrives; Toxicity by
Inhalation (Thresholdfirnit Value): 0.1 ppm; Short-Tern ExposureLimits: 0.5 ppm - 5 min.; 0.2 ppm -
60 min.; Toxicity by Ingestion: LD50 < 50 mg/kg; Lute Toxicity: oral rat LD50 46 mg/kg; oral rabbit
LD, 7 mg/kg; Vapor (Gas) Irritant Characteristics: Vapors cause severe irritation of eyes and throat,
and can cause eye and lung injury. There is no tolerance even at very low concentrations; Liquid or
Solid Irritant Characteristics: Causes smarting of the skin and first-degree chemical burns on short
exposure; may cause second degree chemical burns on short exposure; Odor ThreshoM: 0.21 ppm.
Fire Hazards - Flash Point (deg. F): <O OC; -13 CC; Flammable Limits in Air (a): 2.8 - 31; Fire
Extinguishing Agents: Foam, dry chemical, carbon dioxide; Fire Extinguishing Agents Not To Be Used
Water may be ineffective; Special Hazards of Combustion Products: Poisonous vapor of acrolein is
formed from hot liquid; Behavior in Fire: Vapor is heavier than air and may travel a considerable
distance to a source of ignition and flash back. Polymerization may take place, and containers may
explode in fire; Ignition Temperature (deg. F): 453; Electrical Hazard Data not available; Burning
Rate: 3.8 mm/min.
Chemical Reactivity - Reactivity with Water: No reaction; Reactivity with Common Materials: No
reaction; Stability During Transport: Stable when inhibited; Neutralizing Agents for Aciak and Caustics:
Not pertinent; Pulymerization: Undergoes uncatalyzed polymerization reaction around 200°C. Light
promotes polymerization; Inhibitor of Polymerization: Hydroquinone: 0.10 to 0.25 46.

ACRnAMIDE
Chemical Designations - Synonyms: Acrylic Amide SO%, Propenamide 50%; Chemical Fornula:
C&=CHCOw-H,O.
Observable Characteristics - Physical State (as mrmully shipped): Liquid; Color: Clear; Odor: None.
Physical and Chemical Properties - Physical State at I5 'C and I atm. : Liquid; Molecular Weight:
71 (solute only); Boiling Point at I atm.: Data not available (Vapor Pressure 0.033 atm at 125 "C;
Freezing Point: 183, 84, 357; Critical Temperature: Not pertinent; Critical Pressure: Not pertinent;
Specijic Gravity: 1 .05 at 25 "C; Vapor (Gas) Density: Not pertinent; Ratio of Spec@c Heats of Vapor
(Gas): Not pertinent; Latent Heat of Vaporization: Not pertinent; Heat of Combustion: Not pertinent;
Heat of Decomposition: Not pertinent.
Health Hazards Information - Recomnded Personal Protective Equipment: Safety glasses with side
shields; clean body-covering clothing; rubber gloves, boots, apron as dictated by circumstances; in
absence of proper environmental control, use approved dust respirator; Symptoms Following Exposure:
Has produced central nervous system damage, which is partly reversible. Effects can be produced by
oral or skin contact as well as by injection. Chronic acrylamide poisoning can cause midbrain
disturbance and peripheral neuropathy. Contact with liquid can cause moderate irritation of eyes and
skin and may cause moderate transient corneal injury; General Treatment for Exposure:
INHALATION: if ill effects occur, immediately get patient to fresh air, keep him quiet and warm, and
get medical help. INGESTION: if ingested, immediately give large amounts of water (or milk if
immediately available), then induce vomiting and get medical help. EYES: immediately flush with