Page 95 - Handbook of Hazardous Chemical Properties

CHLOROFORM 85
days; possible systemic manifestations include agitation, coma, contraction of pupils of eyes, loss of
reflexes. External contact causes irritation of the skin and eyes. Ingestion causes agitation, coma,
contraction of pupils of eye, loss of reflexes; General Treatmentformosure: INHALATION: remove
victim from contaminated atmosphere at once; give artificial respiration and oxygen, if necessary;
watch for pulmonary edema for several days. EYES: flush with water; do not rub. SKIN: flush with
water. INGESTION: get medical attention; watch for development of pulmonary edema for several
days; Toxicity by Inhalation (Threshold Limit Value): 0.05 ppm; Short-Tern Exposure Limits: Data not
available; Toxicity by Ingestion: Grade 3; oral LD,, 52 mg/kg (rat); Lute Toxicity: Fatty infiltration of
liver; Vapor (Gas) Irritant Characteristics: Data not available; Liquid or Solid Im‘tant Characteristics:
Data not available; Odor Threshold 0.016 ppm.
Fire Hazards -Rash Point: This is a combustible solid, but in solutions it has a flash point of 244 CC;
Flammable Limits in Air (96): Not pertinent; Fire Extinguishing Agents: Water; Fire Extinguishing
Agents Not To Be Used Not pertinent; Special Hazards of Combustion Products: Irritating hydrogen
chloride may form; Behavior in Fire: Unburned material may become volatile and cause severe skin
and eye irritation; Ignition Temperature: No data; Electrical Hazard No data; Burning Rate: Not
pertinent.
Chemical Reactivity - Reactivity with Water: Reacts slowly, producing hydrogen chloride. The
reaction is not hazardous; Reactivity with Common Materials: Reacts slowly with metals, causing mild
corrosion; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not
pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

CHLOROFORM
Chemical Designations - Synonyms: Trichloromethane; Chemical Formula: CHCI,.
Observable Characteristics - Physical State (as normally shipped) : Liquid; Color: Colorless; Odor:
Pleasant, sweet; ethereal.
Physical and Chemical Properties - Physical State at 15 ‘C and I atm. : Liquid; Molecular Weight:
119.39; Boiling Point at I atm.: 142, 61.2, 334.4; Freezing Point: -82.3, -63.5, 209.7; Critical
Temperature: 506, 263.2, 536.4; Critical Pressure: 790, 54, 5.5; Specific Gravity: 1.49 at 20°C
(liquid); Vapor (Gas) Density: 4.1; Ratio of Specific Heats of Vapor (Gas): 1.146; Latent Heat of
Vaporization: 106.7, 59.3, 2.483; Heat of Combustion: Not pertinent; Heat of Decomposition: Not
pertinent.
Health Hazards Information - Recommended Personal Protective Equipment: Chemical goggles. 50
ppm to 2%: suitable full-face gas mask. Above 2%: suitable self-contained system; Symptoms
Following Exposure: Headache, nausea, dizziness, drunkenness, narcosis; General Treatment for
Exposure: INHALATION: if ill effects develop, get victim to fresh air, keep him warm and quiet, and
get medical attention. If breathing stops, start artificial respiration. INGESTION: induce vomiting and
get medical attention. No known antidote; treat symptoms. EYES: flush with plenty of water for at least
15 min. and get medical attention. SKIN: wash with soap and water, remove contaminated clothing and
free of chemical; Toxicity by Inhalation (Threshold Limit Value): 10 ppm for 10-hour work day; Short-
Term Exposure Limits: 50 ppm for 10 min.; Toxicity by Ingestion: Grade 2; LD,, 0.5 to 5 g/kg; Late
Toxicity: None; Vapor (Gas) Irritant Characteristics: Vapors cause moderate irritation such that
personnel will find high concentrations unpleasant. The effect is temporary; Liquid or Solid Irritant
Characteristics: Minimum hazard. If spilled on clothing and allowed to remain, may cause smarting
and reddening of the skin; Odor Threshold 205-307 ppm.
Fire Hazards - Flash Point: Not flammable; Flammable Limits in Air (96): Not flammable; Fire
Extinguishing Agents: Not pertinent; Fire Extinguishing Agents Not To Be Used Not pertinent; Special
Hazards of Combustion Products: Poisonous and irritating gases are generated upon heating; Behavior
in Fire: Decomposes resulting in toxic vapors; Ignition Temperature: Not flammable; Electrical
Hazard Not pertinent; Bum’ng Rate: Not flammable.
Chemical Reactivity - Reactivity with Water: No reaction; Reactivity with Comn Materials: No
reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent;
Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.