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Chapter 17
                                                        Experiments: Medical
                                                             Breakthroughs or
                                                          Misleading Results?
                                         In This Chapter
                                         ▶ Distinguishing experiments from observational studies
                                         ▶ Dissecting the criteria for a good experiment
                                         ▶ Watching for misleading results
                                                          edical breakthroughs seem to come and go quickly. One day you
                                                    Mhear about a promising new treatment for a disease, only to find out
                                                    later that the drug didn’t live up to expectations in the last stage of testing.
                                                    Pharmaceutical companies bombard TV viewers with commercials for pills,
                                                    sending millions of people to their doctors clamoring for the latest and great-
                                                    est cures for their ills, sometimes without even knowing what the drugs are
                                                    for. Anyone can search the Internet for details about any type of ailment, dis-
                                                    ease, or symptom and come up with tons of information and advice. But how
                                                    much can you really believe? And how do you decide which options are best
                                                    for you if you get sick, need surgery, or have an emergency?

                                                    In this chapter, you go behind the scenes of experiments, the driving force of
                                                    medical studies and other investigations in which comparisons are made —
                                                    comparisons that test, for example, which building materials are best, which
                                                    soft drink teens prefer, and so on. You find out the difference between experi-
                                                    ments and observational studies and discover what experiments can do for
                                                    you, how they’re supposed to be done, how they can go wrong, and how you
                                                    can spot misleading results. With so many headlines, sound bites, and pieces
                                                    of “expert advice” coming at you from all directions, you need to use all your
                                                    critical thinking skills to evaluate the sometimes-conflicting information
                                                    you’re presented with on a regular basis.












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