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                     strategic view of Process Integration is outlined; this includes an
                     overview of the hierarchy of process design, the meaning of
                     performance targets, and the practical issue of identifying heat
                     recovery problems from process flowsheets. These three topics are
                     closely interrelated. Without properly applying the process design
                     hierarchy, the performance targets cannot find a practical application
                     and use. However, the process design hierarchy would be difficult to
                     apply without employing performance targets and estimating upper
                     bounds on process performance or lower bounds on total cost.
                     Meaningful and practically useful heat-integrated designs cannot be
                     obtained without appropriate identification of the heat recovery
                     problem, a process referred to as data extraction. The chapter
                     proceeds to describe the use of Composite Curves to set heat recovery
                     targets, the Problem Table Algorithm for numerical targeting, and
                     the Heat Recovery Pinch. These tools and concepts form the basis of
                     Pinch Technology, defining the thermodynamic capabilities of the
                     heat recovery problems. The more advanced aspects are discussed
                     next; these include threshold problems, targeting multiple utilities
                     via the Grand Composite Curve, and establishing targets for heat
                     transfer area, capital cost, and total cost. There is a short overview of
                     options for modifying the core process (which defines the heat
                     recovery problem) that highlights the usefulness of Pinch Technology
                     and targeting for improving its energy efficiency. The chapter then
                     focuses on the synthesis of Heat Exchanger Networks; the approach
                     mainly follows the Pinch Design Method, but there is discussion of
                     the superstructure-based and hybrid methods used for HEN
                     synthesis. The next step is Total Site Integration, which provides the
                     necessary knowledge for energy recovery over complete industrial
                     complexes and sites.
                        Chapter 5 deals with an extension of PI known as Mass Integration,
                     the most widely used instance of which is Water Integration (WI).
                     The chapter begins with a description of the methodology and bases
                     for minimizing water use and maximizing water reuse, and the
                     importance of legislatively imposed constraints is discussed. Best
                     available techniques are analyzed and recommended for usage, and
                     the concept of a water footprint is described. At this point, the stage
                     is set for the main task: minimizing freshwater usage and wastewater
                     effluents. For this, the methodology of Water Pinch Analysis is
                     introduced. Also described is a related Mass Integration and
                     targeting technique, the material recovery Pinch diagram. The
                     chapter concludes with water minimization using the mathematical
                     optimization approach. Both the WI and the mathematical
                     approaches to optimization are illustrated with case studies.
                        Chapter 6 addresses further PI opportunities that have arisen as
                     the methodology was developed. These include: Hydrogen Networks
                     Design and Management; Oxygen Pinch Analysis; combined analyses
                     (energy-water, oxygen-water, Pinch-emergy, budget-income-time,
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