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not seem to have a great advantage over the system used by Lange and Griffiths [10] and developed by
Lab Connections Inc., and is certainly more complicated and cumbersome. It should also be noted that
if the mobile phase employed contains any solvents, then these will also be extracted by the methylene
dichloride.
Figure 8.25
The Separation of a Mixture of Phenyl Ureas.
Reprinted with permission from G. W. Somsen, E.
W. J. Hooijschuur, C. Goopijer, U. A. Th. Brinkman
and N. H. Velthorst, Anal. Chem., 68(5)(1996)746,
Copyright 1996 American Chemical Society
However, providing the solvents were reasonably volatile, they would be removed in the nebulizing
process. In addition, there must not be sufficient solvent present to render the mobile phase miscible
with the methylene dichloride and prevent the formation of segmented flow.
