Page 195 - Thermodynamics of Biochemical Reactions

BasicBiochemData2

Data and Programs for Biochemical Thermodynamics

Robert A. Alberty
Department of Chemistry 6-2 15
Massachusetts Institute of Technology
Cambridge, MA 02139
alberty @ mit. edu

Abstract: The objective of this package is to give the basic thermodynamic data on a large number of species involved in
biochemical reactions at 298.15 K, 1 bar, and zero ionic strength and show how to use these data to calculate apparent
equilibrium constants K of biochemical reactions at desired pHs and ionic strengths. Biochemical reactions are written in
terms of sums of species, which are referred to as reactants. The thermodynamic properties of reactants are referred to as
transformed properties because the pH is specified. Programs are given for calculating the standard thermodynamic proper-
ties of reactants from the basic data on species. Four tables are included to show how the standard transformed Gibbs
energies of formation and standard transformed enthalpies of formation of 131 reactants depend on pH and ionic strength.
Programs are given for the calculation of apparent equilibrium constants and other thermodynamic properties of reactions by
simply typing in the reaction in the computer. Examples are given of various uses of these tables, including how to plot the
various properties versus pH.

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