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Biological Approach for Removal of Pharmaceutical Pollutants     125



           TABLE 7.2
             Groupings of Pharmaceuticals Identified in Rivers in India

           S. No      River       Presence of Pharmaceutical Compounds  References
            1        Cooum       Triclocarban (6.18 µg/L), Ibuprofen (2.32 µg/L),   Subedi et al.
                                 Antiplatelet carboxylic acid (1.37 µg/L), Atenolol   (2015)
                                    (3.18 µg/L), Amphetamine (0.984 µg/L)
            2        Yamuna      Ampicillin (13.8 μg/L), Ciprofloxacin (1.4 μg/L),   Mutiyar and
                                Gatifloxacin (0.48 μg/L), Sparfloxacin (2.1 μg/L),   Mittal (2014)
                                         Cefuroxime (1.7 μg/L)
           3         Kaveri             Carbamazepine (13.0 ng/L)    Ramaswamy
                                                                     et al. (2011)
           4         Bhavani              Triclosan (139 ng/L)       Ramaswamy
                                                                     et al. (2011)
           5       Kaveri, Vellar,   Naproxen, Diclofenac, Ibuprofen, Ketoprofen, and   Shanmugam
                  and Tamiraparani    acetylsalicylic acid (0.66 μg/L)  et al. (2013)
            6      Vrishabavathi  Erythromycin, Chloramphenicol, and Trimethoprim,   Iyanee et al.
                                 multidrug-resistant pathogenic microorganisms  (2013)



           (Mutiyar and Mittal, 2014). A level of 13.0 ng/L of carbamazepine was found in
           the Kaveri River and 139 ng/L of triclosan in the Bhavani River, a branch of the
           Kaveri (Ramaswamy et al., 2011). Naproxen, diclofenac, ibuprofen, ketoprofen,
           and  acetylsalicylic  acid  up  to  0.66  μg/L  were  found  in  the  Kaveri,  Vellar,  and
           Tamiraparani Rivers (Shanmugam et al., 2013). As well as erythromycin, chlor-
           amphenicol, and trimethoprim, multidrug-resistant pathogenic microorganisms
           were found in the Byramangala tank, supplied by the Vrishabavathi River, which
           contra-indicates numerous anti-infective agents recommended and consumed in
           India (Iyanee et al., 2013). Finally, the presence of abnormal amounts of sulfa-
           methoxazole during rainstorms could be related to the high level of overflow from
           farmland in the surrounding territories.


           7.4.5  pHarMaceuTical process WasTeWaTer
           Water is a basic raw material in pharmaceutical and substance-producing operations;
           reliable and pure water supplies are required for a range of operations including pro-
           duction, material preparation, and cooling. Process water quality administration is
           of extraordinary significance in pharmaceutical fabrication and is also a compulsory
           prerequisite for the cleaning of containers or therapeutic equipment in other medical
           services applications, including water for infusion (WFI). Process wastewaters is a
           term used to characterize wastewater in any industry that originates from the pro-
           cedures taking place in the business. Process wastewaters in these terms cover any
           water that, at the time of assembly or preparation, interacts with the crude materials,
           items, intermediates, by-products, or waste items, which are used in various unit
           operations or procedures.
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