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Biological Approach for Removal of Pharmaceutical Pollutants     123


           conservation of these systems in a given animal group conceivably increases the
           likelihood that these pharmaceuticals will be pharmacologically active in non-target
           living organisms. This method of activity (MoA) idea can be related to all aquatic
           biota that are inadvertently exposed to pharmaceuticals in their natural habitat, along
           these lines raising the hazard of ecotoxicological impacts.

           7.4   PATHWAY FOR PHARMACEUTICAL ITEMS
                GOING INTO THE GROUNDWATER
           In this section, the focus is on various areas where a point source has brought about
           the pollution: landfill, wastewater from a doctor’s facility, septic systems, and waste-
           water effluent from WWTPs. Figure 7.3 shows in detail the pathway of pharmaceu-
           tical products entering the groundwater. Rather than point source contamination,
           which originates from one point, non-point source contamination is characterized
           by the United States Geological Survey (USGS 2015) as a diffuse release of con-
           taminants in nature, and this could be because of the water system, precipitation, or
           snowmelt that conveys contaminants to the recipients.


           7.4.1  lanDfill
           Around the world, the best-known path for the transfer of metropolitan strong waste
           is landfilling. The strong waste may discharge substances into the leachate that later
           enter the receiving environment and might debilitate the biological communities
           (Buszka et al., 2009; Eggen et al., 2010). Landfills are the final repository for various


                     Veterinary drugs               Industrial and hospital
                                                       wastewater
                            Solid waste
                                                 Raw wastewater
                                Landfill/open
                                 dumping      Surface water  Rivers/Oceans
                          Water treatment plants  Ground
                                                            /Lakes/Ponds
                                         water



                                  Soils

                                 Landfill    Septic system
                                              Toilet/Sink
                               Solid waste

                                  Household pharmaceutical
                                        products

           FIGURE 7.3  Pathway of pharmaceutical products entering into the groundwater.
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