Page 138 - Materials Chemistry, Second Edition
P. 138

Biological Approach for Removal of Pharmaceutical Pollutants     119



           TABLE 7.1
           Classifications of Pharmaceutical Products

                  Pharmaceutical
           S. No    Products     Functions/Uses  Compounds and their Molecular Formulae
           1        Antibiotics    Kill bacteria    Ampicillin C 16 H 19 N 3 O 4 S, Amoxicillin
                                                     C 16 H 19 N 3 O 5 S, Chloramphenicol
                                                 C 11 H 12 Cl 2 N 2 O 5 , Clarithromycin C 38 H 69 NO 13 ,
                                                  Sarafloxacin C 20 H 17 F 2 N 3 O 3 , Erythromycin
                                                   C 37 H 67 NO 13 , Sulfapyridine C 11 H 11 N 3 O 2 S,
                                                 Sulfamethoxazole C 10 H 11 N 3 O 3 S, Tetracycline
                                                            C 22 H 24 N 2 O 8
           2       Anesthetics  Abdominal surgery  Lignocaine C 14 H 22 N 2 O, Isoflurane C 3 H 2 ClF 5 O,
                                                   vasoconstrictors (primarily adrenaline)
            3      Antiepileptic  Treatment of epileptic   Carbamazepine C 15 H 12 N 2 O, Primidone
                                    seizures                C 12 H 14 N 2 O 2
           4      Antineoplastics  Kill neoplastic cells  Epirubicin C 27 H 29 NO 11 , Ifosfamide
                                                  C 7 H 15 C l2 N 2 O 2 P, Methotrexate C 20 H 22 N 8 O 5
           5        Antiserum   Treat envenomation          Agglutinins
            6       Blood lipid   Regulation of   Clofibrate C 12 H 15 ClO 3 , Gemfibrozil C 15 H 22 O 3
                    regulators   triglycerides and
                                cholesterol in blood
           7        Hormones    Influence digestion,   Mestranol C 21 H 26 O 2 , Estradiol C 18 H 24 O 2 ,
                                  control sexual   Testosterone C 19 H 28 O 2 , Androstenedione
                                  development                C 19 H 26 O 2
           8       Paracetamol  Pain reliever and fever   Acetaminophen C 8 H 9 NO 2
                                    reducer
           9      Penicillins and   Kill bacteria, treat skin   6-aminopenicillanic acid with a side chain
                  C 16 H 18 N 2 NaO 4 S +  infections, dental   attached to the 6-amino group
                                 infections and ear
                                   infections
           10      Sulfonamides  Treat ulcerative colitis  Benzenesulfonamide C 6 H 7 NO 2 S,
                                                     Methanesulfonamide CH 5 NO 2 S
           11      Enrofloxacin   Treat animals afflicted   Enrofloxacin C 19 H 22 FN 3 O 3
                    (veterinary   with certain bacterial
                   medicaments)    infections
           12       β-Blockers   Treat hypertension  Metoprolol C 15 H 25 NO 3 , Propranolol C 16 H 21 NO 2 ,
                                                 Nadolol C 17 H 27 NO 4 , Pindolol C 14 H 20 N 2 O 2 ,
                                                       Acebutolol C 18 H 29 ClN 2 O 4


           pollutants, since their transformation and removal rates can be compensated by
           their continuous input into the environment. A few compound classes will be
           highlighted, either because the concentrations found in water are high, because
           of their (increasingly) high-volume use, or because of the persistence of these
           compounds. Surface spill-over and direct use in aquaculture can cause the pol-
           lution of marine environments (Huerta et al., 2013). Pharmaceutical compounds
   133   134   135   136   137   138   139   140   141   142   143