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1 6. Applications of Identity Coefficients 113

3 4 5
a/a a/b
6
a/b
FIGURE 6.1. A Pedigree Illustrating Marker Sharing Among Affecteds

6.7 References

[1] Crow JF, Kimura M (1970) An Introduction to Population Genetics
Theory. Harper and Row, New York

[2] Elston RC, Lange K (1976) The genotypic distribution of relatives of
homozygotes when consanguinity is present. Ann Hum Genet 39:493–
496

[3] Fisher RA (1918) The correlation between relatives on the supposition
of Mendelian inheritance. Trans Roy Soc Edinb 52:399–433

[4] Grimmett GR, Stirzaker DR (1992) Probability and Stochastic
Processes, 2nd ed. Oxford University Press, Oxford

[5] Hall JM, Lee MK, Newman B, Morrow JE, Anderson LA, Huey B,
King M-C (1990) Linkage of early-onset familial breast cancer to chro-
mosome 17q21. Science 250:1684–1689
[6] Hodge SE (1984) The information contained in multiple sibling pairs.
Genet Epidemiology 1:109–122
[7] Jacquard A (1974) The Genetic Structure of Populations. Springer-
Verlag, New York
[8] Lange K, Boehnke M (1983) Extensions to pedigree analysis. IV. Co-
variance components models for multivariate traits. Amer J Med Genet
14:513–524

[9] Pericak-Vance MA, Bebout JL, Gaskell PC Jr, Yamaoka LH, Hung
W-Y, Alberts MJ, Walker AP, Barlett RJ, Haynes CA, Welsh KA,