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                   Within a risk analysis, the CODEX Alimentarius Commission has
               developed the concept of quantitative microbiological risk assess-
               ment (MRA), which will complement other quantitative food safety
               targets that are currently under development, such as FSOs and POs
               (Hugas et al. 2007). MRA has been driven by the requirement for
               science-based risk assessment, as well as sanitary and SPS agreements.
               MRA facilitates safe international trade of food and food products
               (van Schothorst 2002).

               10.4.1  Stages in Risk Assessment
               Risk assessment is a well-established method of characterizing the
               impact of foodborne bacteria on the food chain and consists of four
               main stages: hazard identification, exposure assessment, hazard char-
               acterization (or dose-response assessment), and risk characterization
               (Fig. 10. 3).
                   The first stage in the process is identifying hazards. This involves
               identifying the hazard in question and necessitates the collation of all
               relevant data pertaining to the hazard. This stage will usually high-
               light factors that contribute to the survival, mode of transmission,
               and growth of the foodborne pathogen. Hazard identification focuses
               on what can go wrong and how it might happen.
                   During exposure assessment, the pathways by which the hazard
               can reach a host are identified, and the effects of process stages and
               possible critical control points are assessed. Exposure assessment
               evaluates the likelihood of these hazards occurring and the resulting
               implications. Thus, the ultimate goal of exposure assessment is to
               evaluate the occurrence and levels of a hazard in a food at the time of
               consumption (Voysey and Brown 2000).
                   An accurate exposure assessment means that we need accurate
               information on the following: the presence of the pathogen in raw
               ingredients and the effect of food processing, distribution, handling,


                                     Hazard identification



                                     Exposure assessment



                                    Hazard characterization



                                     Risk characterization

               FIGURE 10.3  Stages of risk assessment.
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