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148 5 Membranes in Chiral Separations
processes are the ease of staging (this applies especially to the liquid–membrane
fractionation) and the ease of treating large streams (which is a key advantage of the
MEUF process). In the near future, we expect more of these “hybrid” technologies
to be developed, which will certainly broaden the scope of membrane-based enan-
tioseparations.
List of structures
1 N-alkyl-L-hydroxyproline
2 Propranolol
3 Bupranolol
4 Modified cyclodextrin
5 3,3’-dimethylbis(α,α’-dinaphthyl)-22-crown-6
6 Poly{1-[dimethyl(10-pinanyl)silyl]prop-1-yne} (PDPSP)
7 H-Asp(OcHex)-Leu-Asp(OcHex)-Glu(Obzl)-CH - (DIDE)
2
8 Norephedrine
9 Ephedrine
10 Mirtazipine
11 Salbutamol
12 Terbutaline
13 Ibuprofen
14 -5-cholesteryl glutamate
References
[1] Bayley, C. R., Vaidya, N. A., in Chirality in Industry, The Commercial Manufacture and Applica-
tions of Optically Active Compounds, Collins, A. N., Sheldrake, G. N., and Crosby, J. (eds.), Wiley,
Chichester, 1992
[2] Dorson, W. J. and Pierson, J. S., J. Membr. Sci., 44 (1989) 35
[3] Sourirajan, S., Matsuura, T., Reverse Osmosis/Ultrafiltration, Process Principles, National
Research Council Canada, Ottawa, 1985
[4] Ho, W. S. W., and Sirkar, K. K., Membrane Handbook, Chapman & Hall, New York, 1992
[5] Keurentjes, J. T. F. and Voermans, F. J. M., in Chirality in Industry II, Developments in the Manu-
facture and Applications of Optically Active Compounds, Collins, A. N., Sheldrake, G. N., and
Crosby, J. (eds.), Wiley, Chichester, 1997
[6] Pickering, P. J., Southern, C. R., J. Chem. Biotechnol., 68 (1997) 417
[7] Brice, L. J., Pirkle, W. H., Chiral separations: Applications and Technology, Ahuja, Satinder (eds.)
American Chemical Society, Washington D.C., 1997
[8] Pickering, P. J., Chaudhuri, J. B., Chirality, 9 (1997) 261
[9] Skrzypinski, W., Sierleczko, E., Plucinski, P., Lejczak, B., Pafarski, P., J. Chem. Soc. Perkin Trans.,
2 (1990) 689
[10] Vaidya, A. M., Bell, G., Halling, P. J., J. Membr. Sci., 97 (1994) 13
[11] Victoiria Martinez-Diaz, M., de Mendoza, J., Torres, T., Tetrahedron Lett., 35 (1994) 7669
[12] Heard, C. M., Hadgraft, J., Brain, K. R., Bioseparations, 4 (1994) 111
[13] Scrimin, P., Tonellato, U., Zanta, N., Tetrahedron Lett., 29 (1988) 4967
[14] Pirkle, W.H., Doherty, E. M., J. Am. Chem. Soc., 111 (1989) 4113
[15] Armstrong, D. W., Jin, H. L., Anal. Chem., 59 (1987) 2237
[16] Pietraszkiewicz, M., Kozbial, M., Pietraskiewicz, O., J. Enantiomer, 2 (1997) 319