Page 54 - Color Atlas of Biochemistry

Carbohydrates 45

A. Hyaluronic acid
COO HOCH 2 β COO β HOCH 2 COO HOCH 2
H O H O H O H O H O H O
O H H O H H O H H O
H O OH H 1 3 H 1 O OH H H O OH H
HO H H HO H H HO H H
4
H OH H NHCOCH 3 H OH H NHCOCH 3 H OH H NHCOCH 3

Disaccharide unit
II V VI
IV
I III
[ 3)-β-D-GlcNAc-(1 4)-β-D-GlcUA-(1 4] n

B. Oligosaccharide in immunoglobulin G (IgG)

D-Gal D-GlcNAc
HOCH 2 HOCH 2 Core structure
HO O H O
H H
OH H O OH H
H H H
H OH H NHCOCH 3
HOH C H
2
H O H H O H
D-Man H CH 3
OH O L-Fuc H HO
HOCH 2 HO O HO O N-glycosidic
bond
H O H H OH H
D-GlcNAc H CH 2 HOCH 2 CH 2
OH H
H O H O H O
HO H H H H HN
H NHCOCH 3 HO O OH H O OH H C O
HOH C HO H H H
2
H O H H H H NHCOCH 3 H NHCOCH CH 2
3
D-Man H O D-Man D-GlcNAc D-GlcNAc
OH C
HO O Asn-297
H H

C. Glycoproteins: forms
O-linked N-linked NeuAc NeuAc
NeuAc
Man Man Man Gal Gal
Gal
Man Man Man GlcNAc GlcNAc
GlcNAc
Man Man Man Man

NeuAc Man Man
Gal GlcNAc GlcNAc

GalNAc NeuAc GlcNAc GlcNAc Fuc
O NH NH
Ser Asn Asn Protein

Mannose-rich type Complex type

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.