Page 362 - Elements of Chemical Reaction Engineering Ebook

Chap. 6 Questions and Problems 333

(2) PBA+OA k2 > E+BA
(3) BfPBA k3 > 2BA

Additional information:
Concentration of pure B = 9.8 km01/m3
Concentration of pure. OA = 3.15 km0Vm3
Catalyst concentration = 4 x 10-5 km0l/m3
-
,+-[c;~~]O.S[B]1.7 kl = 1'745 k;r min-1 at 47°C with E, = 18,500 caI/mcil and
rI = -
(l f'K1[0A1)0'7
K, = 64.03 m3/hol
b;Jl

r2 = kz[PBA]0.5[OA]0~6 k, = 0.178 - anin-' at 47°C with E, = 9177 cal/mol

k, = 0.08 min-' at 47°C with E, = 17,132 caYmol and
k3 [PB A]
r, = - K, = 8.064 m3/kmoi
(1 + ,K3[0A])1.0
How should the reaction be carried out (e.g. type of reactor(s>, volume, tem-
perature, feed rate) to produce 100 kmol of oleic acid expoxide (E) per day?
There will be a prize for the solution that meets this criteria and minimizes the
undesirable products. If equipment costs are available they should be included.

P6-26,: A new catalytic pathway for an important intermediate in the productlion of
the nonsteroidal anti-inflammatory drug ibuprofen (e.g., Advil) has been
developed [Chern. Eng. Sci., SI, 10, 1663 (1996)l. The pathway involvles the
hydrogenation of p-isobutyl acetophenone (B) in a solution of methanol con-
taining a HY zeolite catalyst and saturated with hydrogen. The intermediate
products are p-isobutylphenyl ithanol (C), p-isobutylphenylethylmethyl ether
(E) and p-isobutylethyl benzene (F). The reaction scheme is shown below.

(4) E+A--+F+M.

The following rate laws apply to the above equation.