Page 132 - Encyclopedia of Chemical Compounds 3 Vols

H
H H N H
C
C H
H C C N H H

O C H C C C S CH 3
C C O C

H H C N
C CH
O 3
H C O

OH

OTHER NAMES:
See Overview.

FORMULA:
C 16 H 19 N 3 O 5 S
Amoxicillin
ELEMENTS:
Carbon, hydrogen,
nitrogen, oxygen,
sulfur
OVERVIEW
COMPOUND TYPE: KE
Organic Amoxicillin (uh-MOX-uh-sill-in) is also known as
(pharmaceutical) Y D-(-)-alpha-amino-p-hydroxybenzyl penicillin and (2S,5R,6R)-
6-[(R)-(-)-2-amino-2-(phydroxyphenyl)acetamido]-3,3-dimethyl-
STATE: F
Solid A 7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. It
is an off-white crystalline antibiotic, a substance that inhi-
MOLECULAR WEIGHT: C
bits the growth of microorganisms. It is generally available
365.40 g/mol
in the form of the trihydrate (having three molecules of
T
MELTING POINT: S water for each molecule of amoxicillin) with the formula
No data available C 16 H 19 N 3 O 5 S 3H 2 O. Amoxicillin is effective against a number
of disease-causing bacteria, including streptococci, the bac-
BOILING POINT:
terium that cause strep throat, and most strains of pneumo
No data available
cocci, the bacterium that cause pneumonia, gonococci, the
SOLUBILITY: bacterium that cause gonorrhea, and meningococci, the bac-
Soluble in water and
terium that cause meningitis. Amoxicillin works by block-
alcohol; insoluble in
ing the formation of bacteria cell walls. Without cell walls,
most organic solvents
the bacteria die.
Amoxicillin belongs to a group of semisynthetically
produced antibiotics called the aminopenicillins. The term

CHEMICAL COMPOUNDS 81