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 Encyclopedia of Physical Science and Technology  EN016H-959  August 1, 2001  11:6




















                                   Toxicology in Forensic Science






              Olaf H. Drummer
              Monash University



                I. Applications of Forensic Toxicology
                II. Specimens
               III. Chain of Custody
               IV. What Chemicals Should Be Targeted?
                V. Techniques Used
               VI. Initial Tests and Confirmation
              VII. Quality Assurance and Validation
              VIII. Reports
               IX. Interpretation of Toxicological Results
               X. Artefacts in Analysis
               XI. Court Testimony and Expertise








              GLOSSARY                                            physical items such as drug powders, tablets, syringes,
                                                                  etc.
              Amphetamines A class of drugs that act as powerful  Forensic toxicology The application of toxicology to the
                stimulants with actions similar to norepinephrine.  needs of the law.
              Benzodiazepines A class of over 50 drugs that act as mi-  Initial testing The use of screening tests to establish the
                nor tranquilizers and hypnotics and include diazepam,  likely presence of drugs or drug classes in a sample.
                temazepam, flunitrazepam, oxazepam, and alprazolam  Opioids A class of drugs related to morphine, often also
                etc.                                              known as opiates.
              Central nervous system (CNS) The part of the body in-
                cluding the brain and spinal cord.
              Confirmatory testing The use of a second test to con-  TOXICOLOGY in the context of forensic science deals
                firm the intial test such that there is no doubt over the  with the detection of drugs and other chemicals in situa-
                presence of the substance in the sample.        tions involving legal proceedings. This discipline is best
              Ethical drugs Drugs that are available by prescription or  called forensic toxicology; however, the term analytical
                legally over the counter.                       toxicology is also often applied to this subspecialty of tox-
              Exhibits Items brought to a laboratory that form part  icology. A forensic toxicologist is concerned with the de-
                of the evidence in a case; can be tissue specimens or  tection of drugs or poisons in samples and is capable of




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