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Chapter 1 • Basic Neurosciences With Relevance to Electronic Assistive Technology  15



                   Postnatal:

                  •   Meningitis.
                  •   Acquired injury before the age of 2 years.

                   If CP is considered, there are a number of MRI-identified aetiological causes of the
                 nonprogressive disorder of the brain. Damage to the pathways of the brain or white
                 matter occurs in 45%, to the basal ganglia in 13%, focal infarct 7% and congenital mal-
                 formation 10% (NICE Guideline, 2017). White matter damage, including PVL is more
                 common in children born preterm and generally leads to an upper motor neuron dis-
                 order, a picture of high muscle tone, and spasticity, weakness and poor selective control
                 of muscle firing.
                   Basal ganglia damage is generally associated with a fluctuating tone disorder –
                 dyskinetic CP – and is often associated with a perinatal hypoxic/ischaemic event.
                   CP acquired after the neonatal phase is generally associated with infection, particularly
                 following meningitis.
                   When we look and discuss the pattern of CP we describe the following:
                  •   Unilateral or bilateral nature.
                  •   Predominant movement difficulty:
                    •  Tone – high/hyper- (spastic), low/hypo- or mixed dystonic.
                    •  Movement – hyper-, hypo- or dyskinetic.

                   The pattern of movement disorder is dependent on where the primary impairment is
                 within the brain:
                  •   We grade severity of involvement on various functional scales. The most widely used of
                   these focuses on the gross motor abilities of the individual, the Gross Motor Functional
                   Classification System. This scores mobility on a scale of I–V (Palisano et al., 1997):
                    •  I – Independent community walker.
                    •  II – Mild limitation in independent walking, particularly on slopes and stairs.
                    •  III – Independent walking for short distances; assisted walking or wheelchair use
                      mid- to long distance.
                    •  IV – Independent mobility in manual or powered wheelchair; therapeutic walking at
                      best with support.
                    •  V – No independent mobility – dependent on adults for all mobility needs.
                  •   Other scored functional scales focus on areas of communication, nutrition and fine
                   motor ability.

                   There are unsurprisingly a wide variety of comorbidities (clinical difficulties) associ-
                 ated with the impairment of the brain, in particular epilepsy, chest and gastrointestinal
                 problems.
                   Movement, positioning, communication, comfort and sensory challenges for the indi-
                 vidual child or adult are all supported by numerous elements of rehabilitation engineering
                 and electronic assistive technology.
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