Page 299 - Industrial Ventilation Design Guidebook
P. 299

5.3 TOX1CITY AND RISKS INDUCED BY OCCUPATIONAL EXPOSURE TO CHEMICAL COMPOUNDS  255



























                                                               49
                  FIGURE 5.32  Elements of risk assessment and risk management. (used with permission.)


                  to single chemicals is still far from complete, much greater difficulties are
                  encountered in assessing the risks of multiple exposures.


        5.3.2 Exposure to Chemical Substances

                  Among the 10 million known chemical compounds, there are some 50 000
                  which are in common use. Workers are usually exposed to several agents si-
                  multaneously (their interactions are considered in section 5.3.4.2). In addi-
                  tion, many impurities in workplace air are inherently complex mixtures,
                  which may consist of hundreds of different compounds. Mineral oils and
                  wood dusts are examples of common complex mixtures.

                  5.3.2.1 Characterization of Exposures
                      Indoor and Outdoor Exposure to Pollutants
                      Occupational and environmental exposure to chemicals can take place
                  both indoors and outdoors. Occupational exposure is caused by the chemicals
                  that are used and produced indoors in industrial plants, whereas nonoccupa-
                  tional (and occupational nonindustrial) indoor exposure is mainly caused by
                  products. Toluene in printing plants and styrene in the reinforced plastic indus-
                  try are typical examples of the two types of industrial occupational exposures.
                  Products containing styrene polymers may release the styrene monomer into
                  indoor air in the nonindustrial environment for a long time. Formaldehyde is
                  another typical indoor pollutant. The source of formaldehyde is the resins used
                  in the production process. During accidents, occupational and environmental
                  exposures may occur simultaneously. Years ago, dioxin was formed as a by-
                  product of production of phenoxy acid herbicides. An explosion in a factory in
   294   295   296   297   298   299   300   301   302   303   304