Page 432 - Multidimensional Chromatography

424 Multidimensional Chromatography

Figure 15.11 (a) Total ion chromatogram of a Grob test mixture obtained on an Rtx-1701
column, and (b) re-injection of the entire chromatogram on to an Rtx-5 column. Peak identifi-
cation is as follows: a, 2,3-butanediol; b, decane; c, undecane; d, l-octanol; e, nonanal; f, 2,6-
dimethylphenol; g, 2-ethylhexanoic acid; h, 2,6-dimethylaniline; i, decanoic acid; methyl
ester; j, dicyclohexylamine; k, undecanoic acid, methyl ester; l, dodecanoic acid, methyl ester.
Adapted from Journal of High Resolution Chromatography, 21, M. J. Tomlinson and C. L.
Wilkins, ‘Evaluation of a semi-automated multidimensional gas chromatography–infrared–
mass spectrometry system for irritant analysis’, pp. 347–354, 1998, with permission from
Wiley-VCH.

shown in Figure 15.12. In the heart-cut(shown as an inset), taken from 25–30 min,
several of the components are further resolved. In earlier studies, also related to
authenticity determination, Mosandl et al. have described methods for the determi-
nation of several chiral natural product (30).