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Source: Photodetection and Measurement

                                                                                   Chapter
                                                                               10








                                                    Measurand Modulation












           10.1 Introduction
                       In earlier chapters we investigated techniques for optimizing the detection
                       sensitivity of weak optical signals and for achieving high repeatability of
                       measurements of relatively strong signals. The primary technical difficulties
                       addressed were, respectively, noise and stability, which we treated as operating
                       independently. Here we will look at an important measurement situation where
                       the two errors are strongly coupled. This concerns the performance of an instru-
                       ment in detecting very small variations in its measurand, that is, the instru-
                       mental characteristic of limit-of-detection or LOD.
                         Consider first the design of a high-sensitivity on-line scattered light mea-
                       surement system, such as a turbidimeter used for analysis of drinking water
                       (Fig. 10.1a). A high-power modulated light source is projected through the
                       sample to a beam dump, while a high sensitivity receiver collects the scattered
                       light, synchronously detects the source modulation, and displays the turbidity
                       reading V m. During commissioning the water is independently verified to be
                       particle-free, so the relative light scattering efficiency  d and photocurrent  I p
                       should be almost zero. As the signal is so weak, repeated readings of the instru-
                       ment’s display  V m are made and shown to be distributed around zero, as
                       expected. This is represented by the fuzziness of the measurement result at the
                       calibration shown as Day 1.
                         The next day V m is found to have increased by a small amount DV to just
                       above the first measurement value, causing us to ask “has the turbidity
                       actually increased?” Again, repeating the measurement a few times gives the
                       expected variation in results, which suggests that it wasn’t a one-off error. The
                       smallest change in signal DV that can be detected, and hence the LOD of the
                       turbidity or other physical measurand, is clearly a function of the noise level of
                       the detected signal. To be confident that the intensity has changed, for example
                       between the Day 1 and Day 2 measurements, we require DV to be several times
                       greater than the standard deviation of the noise, the measurement uncertainty.

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