Page 490 - Tandem Techniques
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Figure 12.12
The Spectra Obtained for the Separation of a Series of Aromatic Compounds
Reprinted with permission from S. P. Bouffard, J. E. Katon, A. J.
Sommer and N. D. Danielson, Anal. Chem., 66(13)(1994)1937,
Copyright 1994 American Chemical Society.
Thin Layer Chromatography/Mass Spectroscopy
On-line TLC/MS systems must invariably involve either a transport procedure or an in situ desorption
ionization interface. An interesting tandem system, recently reported by Gusev et al. [9], is the
combination of the time of flight mass spectroscopy with thin layer chromatography using matrix
assisted laser desorption. This technique takes advantage of the unique possibilities that time of flight
mass spectroscopy can offer for this type of sample ionization, and was emphasized when the time of
flight mass spectrometer was discussed in chapter 2.
The procedure is diagramatically depicted in Figure 12.13. Aluminum backed plates were employed,
and after the separation was complete, the
