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48  J. M. GOODMAN






















































                               Figure 3.3. Bryostatin 2. Bryostatin 2 (C H O ) is a biologically active marine
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                               natural product which may have useful anti-cancer properties. It was recently
                               synthesised at Harvard by Professor David Evans and his research group. In this
                               illustration, all of the hydrogen atoms are omitted in order to simplify the
                               structure. The lower diagram shows a low energy conformation of bryostatin 2,
                               but it may only be a local minimum and not a global minimum. Many other
                               conformations are accessible at room temperature.
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