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4.5 Impact Categories, Impact Indicators and Characterisation Factors  269

                Considerable progress in the area, mostly in the context of the EU-projects
               OMNITOX 269)  and UNEP/SETAC Life Cycle Initiative, 270)  are discussed in the two
               subsequent Sections 4.5.3.2 and 4.5.3.3. First we take a look at the ‘simpler’ indica-
               tors based on the principle less-is-better, which can also be used with non-regional
               inventory data and be applied without knowledge of special impact mechanisms.
               The method IMPACT2002+ is of special importance for a characterisation of the
               impact categories human toxicity and ecotoxicity, and was developed by an inter-
               national working group chaired by Olivier Jolliet. 271)  It interconnects 14 mid-point
               categories with four damage categories:
               • human health
               • quality of ecosystems
               • climate change
               • resources.
               These ‘Damage Categories’ are also called Safeguard Subjects, Areas of Protection
               and, most ambiguously, Endpoints. 272)  The damage category called climate change in
               IMPACT2002+ should not be confused with the impact category of the same name
               even though they are closely connected.

               4.5.3.2  Human Toxicity

               4.5.3.2.1  Problem Definition  According to Table 4.4 this impact category was
               designated by DIN/NAGUS 273)  as ‘toxic hazard to humans’, by SETAC Europe 274)
               as human toxicological impacts; a similar definition has been given in the Nordic
               Guidelines. 275)  In a second working group of SETAC Europe for impact assessment
               in LCA (WIA-2) 276)  the expression human toxicity is applied.
                The main difficulty of this category, more than those already discussed, is owing
               to the fact that a strictly scientific composite indicator ‘upstream’ in the impact
               hierarchy that is closer to the emissions (mid-point) does not exist. Toxic molecules
               do not have a common attribute which corresponds to the acidic function in the
               case of AP or to the P or N content in the case of the EP respectively. Neither
               measurable physical or chemical parameters exist according to which an impact
               potential, like GWP or ODP could be calculated using theoretical models. There are
               too many different impact mechanisms leading to diseases or groups of diseases

               269) Operational Models and Information tools for Industrial applications of eco/TOXicological
                  impact assessment (OMNITOX). Special edition Int. J. LCA Vol. 9, No. 5 (2004); Larsen et al.
                  (2004) and Molander et al. (2004).
               270) Jolliet et al. (2004); http://lcinitiative.unep.fr; http://www.uneptie.org/pc/sustain/lcinitiative/
                  home/htm;Hauschild et al. (2008) and Rosenbaum et al. (2008, 2011).
               271) Jolliet et al. (2003, 2004).
               272) Assignable damages are called endpoints in (eco) toxicology. For these test procedures or research
                  methods are developed. Known endpoints for example are probabilities of mortality such as
                  LD50 or LC50.
               273) DIN/NAGUS (1996).
               274) Udo de Haes (1996).
               275) Lindfors et al. (1994, 1995).
               276) Udo de Haes et al. (2002).
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