Page 10 - Biodegradable Polyesters

VIII Contents

6.2.1.2 Cross-linked 134
6.2.2 Copolymers and Composites 138
6.2.2.1 Linear 138
6.2.2.2 Cross-linked 140
6.2.3 Polyester-Containing Polyurethanes and Related Composites 142
6.2.4 Blends and Composites 142
6.2.4.1 Linear 144
6.2.4.2 Cross-linked 145
6.2.5 Polymers with Thermosets 145
6.2.5.1 Conetworks 145
6.2.5.2 Semi-Interpenetrating Network 146
6.2.5.3 Interpenetrating Network 148
6.3 Applications 148
6.4 Outlook and Future Trends 149
Acknowledgments 149
References 149

7 Electrospun Scaffolds of Biodegradable Polyesters: Manufacturing and
Biomedical Application 155
Patricia Pranke, Daniel E. Weibel, and Daikelly I. Braghirolli
7.1 Introduction 155
7.2 Preparation of Polyesters for the Electrospinning Method 157
7.3 Improving the Bioactivity of Electrospun Polyesters 160
7.3.1 Surface Modification Techniques 160
7.3.1.1 Wet Chemical Surface Modification 160
7.3.1.2 Plasma 162
7.3.1.3 Ozone 165
7.3.1.4 Ultraviolet Radiation 167
7.3.1.5 Functionalization of Polyester Electrospun Scaffolds with Bioactive
Molecules 170
7.3.2 Pretreatments: Association of Polyesters with Biomolecules before
Electrospinning 172
7.3.2.1 Blends of Polyesters with Other Polymers and/or Biomolecules 172
7.3.2.2 Co-electrospinning and Electrospraying 174
7.4 Applications 175
7.5 Conclusions 180
References 180

8 Systematic Development of Electrospun PLA/PCL Fiber Hybrid Mats:
Preparation, Material Characterization, and Application in Drug
Delivery 191
Hazim J. Haroosh and Yu Dong
8.1 Introduction 191
8.2 Material Preparation and Characterization 193
8.3 Morphological Observations 197