Page 141 - Chemical and process design handbook
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Speight_Part II_B 11/7/01 3:11 PM Page 2.82
2.82 MANUFACTURE OF CHEMICALS
NOH
NH 2 COCl NH 2
+
Cl Cl
(CH ) SO ,
3 2
4
ClCH COCl, heat,
2
sodium hydroxide
CH (-HCl)
CH 3 3
N O N O
H 2
Cl Cl
N N
Diazepam OH
FIGURE 1 Manufacture of diazepam (Valium).
