Page 220 - Color Atlas of Biochemistry
P. 220

Mitochondria        211


                 A. Mitochondrial structure


                               2 µm
                Outer membrane  DNA   Inner membrane      ATP                    Creatine         Enzymes
                                                          synthase               kinase           of
                                                                                                  lipid
                                                                                                  metabo-
                                                                                                  lism


                                                          Transporter


                                                          Enzymes                 Nucleotide      Porin
                                                          of                      kinases
                                                          oxidative
                Cristae                                   metabo-
                                                          lism

                Matrix space
                                                          Respi-
                Intermembrane space                       ratory
                                                          chain
                                                                                Inter-
                                                          Matrix  Inner         membrane          Outer
                                                          space   membrane      space             membrane



                 B. Metabolic functions

                                                                                               Inter-
                                    Pyruvate           Acyl CoA          Carnitine shuttle     membrane
                                                                                               space




                 Cytoplasmic
                 calcium ions       Pyruvate          Acyl CoA                  Urea cycle

                                                                                                   Urea
                               Ca 2                                           NH 3
                                                     β-Oxidation
                Ca 2

                                                                                  –
                                  Acetyl CoA                                  HCO 3
                                                                                                  A
                                                                                                     PP
                                                                                                   ADP
                                    Tri-
                CO 2      CO 2      carboxylic
                                    acid cycle

                                                       ETF                      +
                                                             H O               H
                                                               2
                                                                                                  A
                                                                     A            A                  PP P
                                      N  A                              PP            PP P
                                              Respiratory chain                                    ATP
                                                                        P



                         Inner membrane                                  ATP synthesis
                                            H +     H  +     H  +             H  +
                         Outer membrane
                                                                    O 2



           Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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