Page 234 - Color Atlas of Biochemistry

Biological membranes 225

A. Principle of receptor action

Chemical signals Signal Physical signals
Metabolites Light
Hormones Recipient Electrical impulses
Neurotransmitters Mechanical stimuli
Mediators
Odorants Transmitter
Tastants
Other molecules Activator
Inorganic ions Effector Protein kinase
Ion channel

Cellular response Mediator Cellular response
Protein activated G-protein
by ions receptor substrate

B. Insulin receptor D. T-cell receptor
α2 α1
Insulin Antigen-presenting cell

β2 β1 Tyrosine
kinase
domain

α2 α1

MHC
β2 P P β1 protein
(class I)
P P
β 2 -
Adaptor Adaptor Micro-
protein protein globulin
Receptor
Protein kinase substrate Protein kinase
C. 7-Helix receptors
Viral
peptide

Lipid Receptor
anchor
α-Sub-
unit
GTP
G protein T-cell
β-Sub- receptor
unit
γ-Sub-
unit

Signaling G protein Effector
substance enzyme

GDP
Activated Second
receptor GDP GTP Precursor messenger T-helper cell

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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