Page 236 - Color Atlas of Biochemistry
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Endoplasmic reticulum and Golgi apparatus           227


                 A. Rough endoplasmic reticulum and Golgi apparatus



                  Morphological                                                      Biochemical
                  structures                              Nucleus                    processes

                                                                                     1. Transport
                                                                                     2. Protein synthesis
                                                                                     2. and folding
                                                                                     2. Signal peptide
                  1. rER                                                             2. cleavage
                                                                                     2. Formation of
                  2. Transport                                                       2. disulfide bonds
                  2. vesicle
                                                                                     2. Oligomerization
                                                                                     2. N-Glycosylation
                                  cis                                                  folding
                                  medial
                  3. Golgi complex                                                   3. cis:
                                  trans                                              3. Phosphorylation
                                                                          Membrane   3. medial:
                                  trans-Golgi network                     protein    3. Sugar cleavage
                                                                                     3. Addition of GlcNAc
                  4. Lysosome
                                                                                     3. Addition of
                                                                                     3. Gal and NeuAc
                  5. Secretory                                                       3. trans-Golgi network:
                  5. vesicle                                                         3. Sorting
                                                                                     4. Hydrolysis of
                                                                                     4. macromolecules
                                                                                     5. Proteolysis
                  6. Cytoplasmic
                  6. membrane                                                        6. Exocytosis



                 B. Smooth endoplasmic reticulum

















                                                                                           Steroid
                                        Phospholipids                   Cholesterol        hormones







                  Outside
                                          Calcium store


                  Plasma
                  membrane
                                                                      Xeno-         Metabolites
                  Inside
                                                                      biotics
                                 Ca 2 +
                                                                                   Enzyme systems
                                                                                   of the lipid metabolism




           Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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