Page 288 - Color Atlas of Biochemistry

Blood 279

A. Composition of lipoprotein complexes

Lipoprotein Lipoprotein Composition
coat core
10 nm

VLDL
Chylomicrons
Chylomicron
C-III, B-48, C-II, B-100, C-III, E, C-II
C-II, E, A-I LDL

B-100

Apo-B-100

Characteristic
apoproteins
IDL

B-100, E, C-III

HDL

A-I, A-III, C-III
-3
Apoprotein Lipoprotein Density (g · cm )
Free cholesterol Chylomicrons <0.95
VLDL 0.950 – 1.006
Phospholipid
IDL 1.006 – 1.019
Cholesterol ester
LDL 1.019 – 1.063
Triacylglycerols HDL 1.063 – 1.210

B. Transport functions

Intestine Dietary lipids Endogenous lipids Extrahepatic
tissues
Receptor- Liver
*mediated * *
endocytosis
Cholesterol Cholesterol
LDL
* Fats *
* Fatty acids
Chylomicrons
Cholesterol 2
return
HDL
IDL
Chylomicron
+
remnants
1
HDL
VLDL
1
Muscle
Free Exchange
fatty + of lipids and
acids Adipose tissue Free apoproteins
Free HDL fatty
fatty acids
acids Free
fatty
1 Lipoprotein lipase 2 Lecithin-cholesterol acyltransferase acids
3.1.1.34 (LCAT) 2.3.1.43

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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