Page 348 - Color Atlas of Biochemistry

Muscle 339

A. Cori and alanine cycle

Liver Blood Muscle
Storage
Glucose Glucose Glucose
3.70-5.18
mM
Glycogen Glucose 6 P Glucose 6 P Glycogen

4 1
6 ATP 2 ATP
Pyruvate Pyruvate Pyruvate Protein
0.02-0.07
N A mM N A
3 3
N A N A Amino
acids
Lactate Lactate Lactate
Urea 0.74-2.40 [NH ]
2
mM
2 2

Alanine Alanine Alanine
0.33-0.61
mM
NADH/NAD + NADH/NAD +
quotient low quotient high

1 Glycolysis
Alanine cycle Plasma concentration 2 Transamination
in adults
Cori cycle
3 Lactate dehydrogenase
1.1.1.27
4 Gluconeogenesis

B. Protein and amino acid metabolism

Blood Muscle breaks Muscle Energy
down reserve in
branched-chain prolonged
amino acids Protein hunger
Testosterone
Anabolic Cortisol
agents
Val Leu Ile
0.25 0.16 0.08 Amino acids
mM mM mM

Ala Gln Amino acids [NH ]
0.42 0.65 Ala, Gln 2
mM mM
Synthesis Degradation

Tri-
carboxylic Energy gain
Plasma acid
concentration cycle

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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