Page 352 - Color Atlas of Biochemistry
P. 352

Connective tissue       343


                 A. Functions of calcium                         B. Bone remodeling

                                                                     Osteoblast         Calcitriol
                                                                                        Calcitonin
                              Mineralization

                                                 Muscle              Ca 2                       Precursor
                                                 con-                                           cells
                                                 traction
                                                                                              Parathyroid
                 Signal                                              Hydroxy-  Collagen I     hormone
                 transduction                                        apatite
                                    Ca 2
                                    Ca 2
                                                               Growth                           Estrogens
                                                               factors

                                               Nerve                         H
                                               conduction                                  Cyto-
                 Exocytosis                                                                kines




                                                                             H
                                                                                                Precursor
                                                 Protein                                        cells
                                                 function
                                                                      HCO 3      H 2 O


                               Ca 2                                         CO 2
                               complex
                                                                     Osteoclast        Calcitonin

                 C. Calcium homeostasis
                                                              Calci-
                                            600 – 900mg                  Calcitriol   1000000 mg    Stock
                                                              tonin
                      1000 mg · d -1

                                                                           oder
                                                                                          Hydroxy-
                  Parathyroid hormone                              500 mg · d -1          apatite
                                                                   500 mg · d -1



                     Calcitriol                                                                  Bone
                                                              Calci-      Parathyroid
                                                              tonin       hormone

                                                                                    Filtration   Kidney
                             300mg · d -1
                           till 150mg · d -1
                                                                10 000 mg · d -1
                                                                 9 850 mg · d -1


                                                                                    Resorption

                                                              Calci-     Parathyroid
                  850mg · d -1                                triol      hormone


                    Intestine                   Blood                                           150 mg·d -1


           Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
           All rights reserved. Usage subject to terms and conditions of license.
   347   348   349   350   351   352   353   354   355   356   357