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1  Introduction  137



































                  FIG. 1
                  Examples of impaired/ungradable images. (A) Poor focus and clarity due to overall haze.
                  (B) Poor macula visibility due to uneven illumination. (C) Poor optic disc visibility due to
                  total blink. (D) Edge haze due to pupillary restriction. (E) Dust and dirt artifacts on the lens
                  image capture system (near the center). (F) Lash artifact.
                  From J.M. Pires Dias, C.M. Oliveira, L.A. da Silva Cruz, Retinal image quality assessment using generic image
                                                       quality indicators, Inf. Fusion 19 (2014) 73–90.


                  these different judgements of image quality, given that automated algorithms are
                  normally evaluated against subjective human evaluation [1]. Non-clinical applications
                  of retinal fundus imaging include analysis for biometric identification, but this is
                  beyond the scope of the applications described in this chapter.
                  1.2.1   Screening for diabetic retinopathy
                  Diagnostic image quality is important in scenarios where individual clinicians judge
                  images to ascertain the ophthalmic health of the patient. For example, a clinician
                  may examine a fundus image to ascertain if a patient has glaucoma, paying close
                  attention to the optic disc area. Optical coherence tomography images may be
                  examined to diagnose diabetic macular oedema. To make a clinical diagnosis which
                  includes the use of information from images, it is important for the image to be of
                  high quality over areas of interest where abnormalities may be expected. In addition
                  to clinical diagnosis on individual patients in a clinic setting, a major requirement
                  for assessment of image quality in a diagnostic application is related to screening
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