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356   Control theory in biomedical engineering


          application in the medical industry. One of the biggest challenges for soft and
          flexible tubular MIS equipment is the load bearing capacity and the ability to
          transform from a flexible compliant device into a stiff and rigid device when
          required. Currently available methods of achieving tunable stiffness are
          either not suited for fast-changing applications or require high temperature
          and pressure applications, which may pose a safety risk when being used
          inside human bodies. Furthermore, the change in stiffness happens in bulk
          across the device, making it difficult to selectively stiffen certain regions
          independently. Instead, we theorize and design a completely novel means
          of achieving tunable stiffness using auxetic materials.
             We first tested the method of jamming using auxetic materials to achieve
          a change in stiffness. We also created folding patterns that exhibit stiffness
          tunability using kirigami and origami methods. These new methods are
          compatible with our existing tendon-driven mechanism and provide an
          integrated actuation and stiffness modulation method. These methods are
          safe and suitable for biomedical applications where the stiffness can be iso-
          lated to specific regions.



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