Page 64 - Illustrated Pocket Dictionary of Chromatography
P. 64
DYNAMIC RANGE 59
The dynamic range for a detector includes non-linear portions of the response
versus concentration plot. The limit to the dynamic range is that there must be a
quantitative difference in the response of two different concentrations. On the low-
concentration part of the range the system noise is the limiting factor. On the high-
concentration part of the range the saturation of the detector, solubility of the
analyte, or chromatographic overloading of the system may be the limiting factors.
In fluorescence work self-absorption is also a potential factor.
