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FABLE 5.8(b) Case-control Studies of Urinary Bladder Cancer among Workers in the Printing Industry 12

                                                                                      No. of
                                                                                      exposed
                  Reference,                                                          cases/   Odds
                  country          Type of controls  Exposure                Sex      controls  ratio  95% Ci  Comments

                          18
                  Najem et al. USA  Hospital-based, tobacco-  Printing industry (a 1 year)  M + F  7/5  2.7  0.8-9.6  Crude odds ratio
                                     related heart diseases
                                     and neoplasms
                                     excluded
                         19
                   Cartwright  United  Hospital-based, non-  Printers (exposed to  M +F  18/NG  3.1    1.4-6.8  Adjusted for type of case
                    Kingdom          malignant diseases  ink-fly from high-speed presses)                        (incident or prevalent)
                                                                                                                 and sex
                            20                                                                        0.7-1.7  Crude odds ratio
                   Silverman et al.  Population-based  Printing industry (ever)  M     50/45    1.1
                    USA                              Printers (ever)         M         6/2      3.0   0.6-14.8
                             21                                                                 0.9   0.5-1.5  Adjusted for age,
                   Schoenberg et al.  USA  Population-based  Printing workers (ever)  M  20/38
                                                     Printing ink (self -reporting)  M  42/53   1.6    1.0-2.5   smoking, and other
                                                                                                                 employments
                                22                                                                    P0.05    Against other cancers;
                   Baxter and McDowall  Other cancers  Printers (stated on death certifi-  M  21/NG  1.5
                    United Kingdom  All causes of death  cates)                                 1.2    P0.05     matched on residence.
                                                                                                                 year of death, age
                            23                                                                  3.1    1.1-8.9  All controls Prostate cancer
                   Brownson et al.  Population-based, other  Printing machine  M       7/8
                                     non-smoking-related  operators (longest-held job)  M  7/6  2.3    0.8-7.2   excluded
                            25  26                                                     37/77    0.8    0.5-1.2  Adjusted for smoking; fre-
                   Silverman et al. -  Population-based  Printer (ever)      M (white)
                    USA                                                      F         1/10     0.2    <0.1-1.4  quency matching for age
                                                                                                                 and geographic
                                                                                                                 area
                           27                                                                   5.0    1.3-19.6  Crude odds ratio
                   Kunze et al.    Hospital-based, non-neo-  Printing industry (ever)  M  11/3
                    France           plastic diseases of the  Printing worker (ever)  M  7/3    3.0    0.7-13.8
                                     lower urinary tract
                           28                                                                   0.9    0.5-1.5  Adjusted for age, hospital
                   Cordier et al,   Hospital-based, neoplas-  Printing and publishing industry  M  26/28
                    France           tic, respiratory and  (ever)                                                residence, smoking
                                     urological conditions  Printers         M         14/9     1.5    0,6-3.5
                                     excluded
                   Siemiatycki et al,~ , 9  Population and hospital-  Printing and publishing industry  M       Adjusted for age, iamilv  1
                    Canada           based, other cancers,  < 10 years                 2/NG     0,3    0.1-1.2   UK-omc, smoking, voftei
                                     excluding lung and      a: 1 0 years Photo-       11 /NG   1,9    0.9-3.9   tonsumptiou, elhnK.it>,
                                     kidney sites    graphic products                  4/NG     3.0    0,9-10.1  respondent static
                                                     {substantial exposure)
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