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occurs  Energy  solvent  inhibitors  and  Washing  residual  degradation  wastewater  usually  energy  solvent  eliminate  low  degradation  (Continued)



              usually  corrosion  used.  is  for  of  temperature  consumed  high.  is  the  causes  is  high  residual  to  enzymatic  fermentation  with  period  also

              are  Severe  catalyst  high  is  Formation  high  at  usually  cost  remove  biomass  solvents  with  The  out  to  Cellulose  significant
              solvents  acid  consumption  inevitable  are  chemical  to necessary  and  which  the  of  complicated  consumption.  washed  be  inhibition  or  pretreatment


              Organic  expensive.  when  recovery.  is  Oxidants  the  is  oxidants  products,  effluent  Recovery  must  its  hydrolysis  Long  efficiency.  undergoes




                       be    lignin  is   of     thus  to            little
                  lignin.  can                              increased.  inhibitors  or  no

              of  cellulose,  and  greatly  is  solvents  or  of  of  digestibility  removal  and  cellulose  networks,  cellulose  be  Can  pretreatment  of  no  mild  and
              fractionation  sugars,  digestibility  Organic  distillation  removal  expose  significant  hemicelluloses  of  crystalline  cellulose.  mild  Cellulose  greatly  is  formation  requirement,  requirement,  conditions,  pollution




              a  obtain  to  by  high  a  significantly  Cellulose  enhanced  a  hydrogen-bonding  under  little
              achieve  biomass  hemicellulosic  Cellulose  improved.  recycled  extraction  achieve  cellulose.  greatly  achieve  and  lignin  deconstruction  converting  amorphous  operated  conditions.  hydrolyzability  or  energy  chemicals  pretreatment  environmental


              Can            Can  and     Can                 No     Low


                     of  is     thus  at     of
                or   removal  structure  particle  fiber  and  increasing  liberated  is  white-,  pretreat  lignin  increasing
              pretreat  acid  of  is  reduced  cellulose  lignin  hemicelluloses,  is  delignification  dissolve  precipitation  of  undergoes  of  cellulose  depolymerized  as  to  fungi  of

              to  Biomass  significant  wall  of  oxidize  and  size  to  by  addition  removal  such  degradation  thus
              solvent  addition  catalysts.  with  Cell  with  liberation  to  degrade  particle  Cellulose  of  solvents  followed  by  Biomass  and  and  microorganisms,  soft-rot  hemicelluloses,  porosity

              organic  with  biomass  delignified  hemicelluloses.  deconstructed  and  oxidants  partially  reducing  porosity.  degree  high  cellulose  biomass  cellulose  antisolvents.  delignification,  hemicelluloses,  decrystallized  and brown-,  with  biomass  substrates


              Using  alkaline  size  Using  the  a  Using  the    pretreatment  Using  and  the







              Catalyzed  organosolv  pretreatment  Oxidative  pretreatment  Cellulose  solvent based  pretreatment  Biological  Microbial  pretreatment
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