Page 261 - Multidimensional Chromatography

256 Multidimensional Chromatography

Reference 30 42 36 63 35 26 17 27 25 24 16 64 18 19 65 33

c
Detection UV and MS–MS UV UV UV UV UV EC UV UV UV UV Flu UV UV EC UV or Flu

b
Subsequent LC mode(s) C18; C8 Chiralcel OJ C18 ion-pair C18 C18 C18 C18 C18 C8 CIEX CIEX; CIEX C18 C18 C1 AIEX C18

(continued) First LC mode b phenyl silica ion-pair C18 C18 ion-pair C18 AIEX CN CIEX CIEX C8 C18 C18 CN C18 ion-pair C18 micel C8 or CN

Table 11.1 Sample a preparation liq–liq extraction liq–liq extraction liq–liq extraction deproteination liq–liq extraction SPE liq–liq extraction SPE SPE ultrafiltration ultrafiltration liq–liq extraction none none acidification, centrifugation none

Sample matrix equine plasma/urine human plasma/urine human plasma/urine rat plasma human plasma human urine plasma human dog plasma human plasma human plasma human plasma human serum/urine urine rat human urine urine human human serum/plasma

Analyte(s) Methandrostenolone and its metabolites Metyrapone Phenyl- propanololamine Probenicid Propanolol Methotrexate Remoxipride metabolite Ro 23-7637 Ro 24-0238 Ropivacaine Sameridine TCV-116 and its metabolites Tipredane metabolites Vanillylmandelic acid Various drugs