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CHAPTER 10





                                                            SpectRx NIR



                                                               Technology








                     10.1  An Introduction to SpectRx NIR Technology
                          This section presents certain theoretical aspects that apply to the
                          SpectRx  FFT NIR Spectroradiometer. It is intended for readers who
                                 1
                          desire to acquire the working knowledge of the SpectRx™ system,
                          shown in Fig. 10.1, in order to better understand its applications. The
                          SpectRx™ system is an analytical system that can be implemented on
                          pharmaceutical and medical production lines, Fig. 10.2. The System
                          measures the chemical compositions and active ingredients of phar-
                          maceutical tablets, capsules, and gels, Fig. 10. 3.
                             While it is technically impossible for the SpectRx™ NIR system to
                          analyze or detect metallic substances, it however, detects and ana-
                          lyzes the organic compound deposited on the metallic surfaces such
                          as the stainless steel medical stents, Fig. 10.4.  When different identi-
                          cal pharmaceutical samples are taken from different batches at a dif-
                          ferent time or production location, the SpectRx™ NIR system pro-
                          vides identical spectra as illustrated in Fig. 10.5.
                             Those who are already familiar with FFT-NIR technology may
                          want to use it as a refresher. The instruments and samples of its appli-
                          cations are also presented.


                     10.2 Abbreviations—Nomenclature
                             ADC           Analog-to-digital converter
                             DSP           digital signal processor
                             EMI           electromagnetic interference
                             FFT           fast Fourier transform

                             FOV           field of view
                             FFTIR         Fourier transform near infrared
                          1  Proprietary of American SensoR , Inc.
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