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192        Part III: Analyzing Variance with ANOVA



                                In this chapter, first I give you an example of when you’d need to use a two-way
                                ANOVA. Then I show you how to set up the model, make your way through the
                                ANOVA table, take the F-tests, and draw the appropriate conclusions.


                      Setting Up the Two-Way ANOVA Model



                                The two-way ANOVA model extends the ideas of the one-way ANOVA model
                                and adds an interaction term to examine how various combinations of the
                                two factors affect the response. In this section, you see the building blocks of
                                a two-way ANOVA: the treatments, main effects, the interaction term, and the
                                sums of squares equation that puts everything together.


                                Determining the treatments


                                The two-way ANOVA model contains two factors, A and B, and each factor has
                                a certain number of levels — say i levels of Factor A and j levels of Factor B.
                                In the drug study example from the chapter intro, you have A = drug dosage
                                with i = 1, 2, or 3, and B = number of times taken per day with j = 1 or 2. Each
                                person involved in the study is subject to one of the three different drug dos-
                                ages and will take the drug in one of the two methods given. That means you
                                have 3 * 2 = 6 different combinations of Factors A and B that you can apply
                                to the subjects, and you can study these combinations and their effects on
                                blood pressure changes in the two-way ANOVA model.

                                Each different combination of levels of Factors A and B is called a treatment in
                                the model. Table 11-1 shows the six treatments in the drug study. For example,
                                Treatment 4 is the combination of 20mg of the drug taken in two doses of
                                10mg each per day.



                                   Table 11-1              Six Treatment Combinations
                                                            for the Drug Study Example
                                  Dosage Amount          One Dose Per Day      Two Doses Per Day
                                  10mg                   Treatment 1           Treatment 2
                                  20mg                   Treatment 3           Treatment 4
                                  30mg                   Treatment 5           Treatment 6














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