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World champion chemists  57



                                 not certain that computers will beat people. However, the odds are stacked
                                 in favour of the computer, which will be able to develop and optimise many
                                 more routes than it is possible for synthetic chemists to consider directly.
                                 How difficult is organic synthesis? We will be taught the answer by the
                                 computers which extend the art beyond the heights reached by human
                                 scientists.


                                 3.1 Further reading

                                 Dirac, P. A. M. 1929 Quantum mechanics of many-electron systems. Proc. R.
                                    Soc. Lond. A 123, 714–733.
                                 Pauling, L. 1945 The nature of the chemical bond. Ithaca, New York: Cornell
                                    University Press.
                                 Goodman, J. M. 2000 Solutions for chemistry: synthesis of experiment and
                                    calculation. Phil. Trans. R. Soc. Lond. A 358, 387–398.
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