Page 166 - Advances in Forensic Applications of Mass Spectrometry - Jehuda Yinon

1522_C04.fm Page 149 Thursday, November 13, 2003 9:54 AM

Forensic Applications
of Isotope Ratio Mass 4

Spectrometry

WOLFRAM MEIER-AUGENSTEIN
RAY H. LIU

Contents
4.1 Introduction
4.1.1 Convention
4.1.2 Variations in Stable Isotope Contents
4.1.3 Discrimination Power
4.2 Instrumentation
4.2.1 Introduction
4.2.2 Dual-Inlet Isotope Ratio/Mass Spectrometry (IRMS)
4.2.3 Continuous-Flow IRMS
4.2.3.1 Bulk Stable Isotope Analysis (BSIA)
4.2.3.2 Compound Specific Isotope Analysis (CSIA)
4.2.3.3 Hyphenated CSIA Systems
4.3 Isotope Dilution
4.4 Sample Differentiation
4.4.1 Detection of Adulteration in Food Products
4.4.2 Dietary Composition as a Basis for Sample
Differentiation
4.4.3 Drugs
4.4.3.1 Marijuana
4.4.3.2 Coca Leaves
4.4.3.3 Heroin, Morphine, and Cutting Agents
4.4.3.4 Synthetic Drugs
4.4.4 Antidoping Testing
4.4.5 Explosives
4.5 Stable Isotope Coding as a Tracing Mechanism:
Methamphetamine Example
References

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© 2004 by CRC Press LLC
© 2004 by CRC Press LLC